Case report: combined pattern thyroid carcinoma

Thyroid cancer accounts for approximately 3% of all new diagnoses per year globally.1 Papillary thyroid carcinoma (PTC) is the most common type, followed by follicular (FTC).1 Recently, simultaneous appearance different histological variants in same patient has been reported, being called combined pattern cancer, mixed tumors, hybrid tumors or compound gland.2 Epidemiologically, reported less than 2% cases, it presents proportion men and women, age presentation between 18 45 years.3 Different associations are found, including carcinomas: a) medullary (CMT) PTC; b) PTC fasciitis-like stroma; c) CPT CFT; even combinations CMT, CFT.4 Several studies suggest a more aggressive clinical behavior, which may be related to coexistence multiple patterns variants, with early detection rapid treatment vital importance. It based on surgical treatment, moderate-high dose radioiodine TSH suppression (<0.1mIU/L).4 This achieves cure rate up 66% survival three years after diagnosis 90% 10 80% 95%.